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To further verify whether OGD treatment could cause endothelial cell senescence, -galactosidase (SA--gal) staining was performed on the endothelial cells treated with OGD

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The Firmicutes/Bacteroidetes (F/B) ratio is commonly used as an indicator of gut microecological health status, and significant alterations in this ratio are associated with obesity, metabolic syndrome, and inflammatory diseases (Magne et al., 2020)

doi: 10.1136/jitc-2023-007402 95 DingHLiuNWangYAdamSAJinJFengWet al

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In summary, niacin is essential to the biochemistry of the nervous system, contributing to energy metabolism, neurotransmitter synthesis, such as serotonin and dopamine, antioxidant activities, and DNA repair (3, 11, 13, 56)